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Anti-HIF1A, Polyclonal [HIF1A]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets HIF1A
Reactivity Human and Mouse
Relevance Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. 
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Molecular Weight (kDa) 92.670 (Isoform1) and 82.69 (Isoform2).
Research Area Cancer, Cardiovascular, Epigenetics & Nuclear Signalling, Metabolism

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