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Info
Applications | ELISA IF WB |
Antigen/Gene or Protein Targets | HIF1A |
Reactivity | Human and Mouse |
Relevance | Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. |
Host | Rabbit |
Immunogen | 3 synthetic peptides (human) conjugated to KLH |
Molecular Weight (kDa) | 92.670 (Isoform1) and 82.69 (Isoform2). |
Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling, Metabolism |
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