Anti-ErbB3 [RTJ2]
Invented at
- Datasheet
- References (12)
- Inventor Info
Info
| Catalogue Number | 151158 |
| Applications | ELISA FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | ErbB3 (Her3) |
| Reactivity | Human |
| Relevance | The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB3 is normally found in non-dividing differentiated epithelial cells, neurones and hepatocytes. It has approximately 80% prevalence in a wide variety of tumours of the gastro-intestinal tract, and approximately 20% prevalence in breast cancer. |
| Host | Mouse |
| Immunogen | Synthetic peptide of human ErbB3 |
| Subclass | IgG1 |
| Myeloma Used | NS0 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS. |
| Research Area | Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction |
References: 12 entries
Almadori et al. 2010. Eur J Cancer. 46(6):1144-52. PMID: 20149638.
Anagnostou et al. 2010. Cancer Epidemiol Biomarkers Prev. 19(4):982-91. PMID: 20332259.
Analytic variability in immunohistochemistry biomarker studies.
Europe PMC ID: 20332259
Prognostic significance and clinical relevance of the expression of the HER family of type I receptor tyrosine kinases in human laryngeal squamous cell carcinoma.
Europe PMC ID: 20149638
Okwueze et al. 2007. J Invest Dermatol. 127(5):1030-41. PMID: 17124505.
Modulation of porcine wound repair with a transfected ErbB3 gene and relevant EGF-like ligands.
Europe PMC ID: 17124505
Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.
Europe PMC ID: 9771476
Rajkumar et al. 1995. Int J Oncol. 6(1):105-9. PMID: 21556509.
Prevalence of C-erbb3 expression in squamous-cell carcinomas of the cervix as determined by the monoclonal-antibody rtj2.
Europe PMC ID: 21556509
Benterud et al. 1976. Tidsskr Nor Laegeforen. 96(31):1647-8. PMID: 982398.
[Hereditary angioneurotic edema]
Europe PMC ID: 982398
Add a reference
References: 12 entries
Almadori et al. 2010. Eur J Cancer. 46(6):1144-52. PMID: 20149638.
Anagnostou et al. 2010. Cancer Epidemiol Biomarkers Prev. 19(4):982-91. PMID: 20332259.
Analytic variability in immunohistochemistry biomarker studies.
Prognostic significance and clinical relevance of the expression of the HER family of type I receptor tyrosine kinases in human laryngeal squamous cell carcinoma.
Okwueze et al. 2007. J Invest Dermatol. 127(5):1030-41. PMID: 17124505.
Modulation of porcine wound repair with a transfected ErbB3 gene and relevant EGF-like ligands.
Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.
Rajkumar et al. 1995. Int J Oncol. 6(1):105-9. PMID: 21556509.
Prevalence of C-erbb3 expression in squamous-cell carcinomas of the cervix as determined by the monoclonal-antibody rtj2.
Benterud et al. 1976. Tidsskr Nor Laegeforen. 96(31):1647-8. PMID: 982398.
[Hereditary angioneurotic edema]
Add a reference