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Anti-ErbB3 [RTJ2]


Catalogue Number 151158
Antigen/Gene or Protein Targets ErbB3 (Her3)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB3 is normally found in non-dividing differentiated epithelial cells, neurones and hepatocytes. It has approximately 80% prevalence in a wide variety of tumours of the gastro-intestinal tract, and approximately 20% prevalence in breast cancer.
Host Mouse
Immunogen Synthetic peptide of human ErbB3
Subclass IgG1
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS.
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 6 entries

Almadori et al. 2010. Eur J Cancer. 46(6):1144-52. PMID: 20149638.

Anagnostou et al. 2010. Cancer Epidemiol Biomarkers Prev. 19(4):982-91. PMID: 20332259.

Okwueze et al. 2007. J Invest Dermatol. 127(5):1030-41. PMID: 17124505.

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Rajkumar et al. 1995. Int J Oncol. 6(1):105-9. PMID: 21556509.

Benterud et al. 1976. Tidsskr Nor Laegeforen. 96(31):1647-8. PMID: 982398.

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