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Anti-ICAM1 [15.2]


Catalogue Number 151036
Applications FACS IHC IP Fn
Antigen/Gene or Protein Targets ICAM1 (CD54)
Synonyms Intercellular Adhesion Molecule 1; Major Group Rhinovirus Receptor; ICAM-1; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; P3.58; CD54; BB2
Reactivity Human
Relevance ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18).
Host Mouse
Immunogen Rheumatoid synovial cells and human monocytes.
Subclass IgG1
Positive Control Tonsil
Molecular Weight (kDa) 85-115
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions E4 +10% FCS
Strain Balb/c
Research Area Adhesion, Cardiovascular, Immunology, Stem Cell Biology

References: 7 entries

Vásquez et al. 2016. Microbes Infect. :. PMID: 27717894.

Novotny et al. 2016. Cell Microbiol. :. PMID: 26857242.

El-Bikai et al. 2010. Arthritis Res Ther. 12(5):R201. PMID: 20977750.

Conway et al. 2010. Am J Physiol Heart Circ Physiol. 298(2):H367-74. PMID: 19915176.

Lauriello et al. 2005. Acta Otorhinolaryngol Ital. 25(5):284-91. PMID: 16602327.

Stanley et al. 2000. Biochem J. 351(Pt 1):79-86. PMID: 10998349.

Dransfield et al. 1992. J Cell Biol. 116(6):1527-35. PMID: 1541641.

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