Anti-Cdk1 [3E1.1]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151049 |
| Applications | WB |
| Antigen/Gene or Protein Targets | Cyclin Dependent kinase 1 (Cdk1, Cdc2) |
| Synonyms | Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1 |
| Reactivity | Xenopus laevis |
| Relevance | Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells. |
| Host | Mouse |
| Immunogen | A carboxy-terminal fragment starting at methionine 85 of Xenopus laevis p34 cdc2. |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Research Area | Cancer, Cell Cycle, Cell Type or Organelle Marker, Neurobiology |
References: 2 entries
Kobayashi et al. 1991. Cold Spring Harb Symp Quant Biol. 56:437-47. PMID: 1840257.
Cyclins and their partners during Xenopus oocyte maturation.
Europe PMC ID: 1840257
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References: 2 entries
Kobayashi et al. 1991. Cold Spring Harb Symp Quant Biol. 56:437-47. PMID: 1840257.
Cyclins and their partners during Xenopus oocyte maturation.
Add a reference
