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Anti-Cdk1 [3E1.1]


Catalogue Number 151049
Applications WB
Antigen/Gene or Protein Targets Cyclin Dependent kinase 1 (Cdk1, Cdc2)
Synonyms Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1
Reactivity Xenopus laevis
Relevance Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells.
Host Mouse
Immunogen A carboxy-terminal fragment starting at methionine 85 of Xenopus laevis p34 cdc2.
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Research Area Cancer, Cell Cycle, Cell Type or Organelle Marker, Neurobiology

References: 1 entry

Kobayashi et al. 1991. Cold Spring Harb Symp Quant Biol. 56:437-47. PMID: 1840257.

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