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Anti-Cytochrome P450 4A2, 4A3 [Clo4]


Catalogue Number 151038
Applications ELISA IP WB
Antigen/Gene or Protein Targets Cytochrome P450 4A2, 4A3, CYP4A2, CYP4A3
Reactivity Rat
Relevance The CYP2 family are part of the microsomal drug metabolising system that is responsible for the oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
Host Mouse
Immunogen Rat liver cytochrome P450 4A2 and 4A3
Subclass IgG2a
Molecular Weight (kDa) 51.5/52.0
Recommended Growing Conditions DMEM + 5% FCS.
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

References: 1 entry

Lukaszewicz et al. 2013. Clin Sci (Lond). 124(5):333-42. PMID: 22938512.

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