Anti-Cytochrome P450 4A2, 4A3 [Clo4]
Invented by Prof Roland Wolf from University of Dundee
Invented at University of Dundee
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151038 |
| Applications | ELISA IP WB |
| Antigen/Gene or Protein Targets | Cytochrome P450 4A2, 4A3, CYP4A2, CYP4A3 |
| Reactivity | Rat |
| Relevance | The CYP2 family are part of the microsomal drug metabolising system that is responsible for the oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels. |
| Host | Mouse |
| Immunogen | Rat liver cytochrome P450 4A2 and 4A3 |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 51.5/52.0 |
| Recommended Growing Conditions | DMEM + 5% FCS. |
| Notes | This reagent was created through a research collaboration between Cancer Research UK and Syngenta Crop Protection AG. |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
References: 2 entries
Lukaszewicz et al. 2013. Clin Sci (Lond). 124(5):333-42. PMID: 22938512.
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats.
Europe PMC ID: 22938512
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References: 2 entries
Lukaszewicz et al. 2013. Clin Sci (Lond). 124(5):333-42. PMID: 22938512.
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats.
Add a reference
Inventor Information
Inventors
|
Prof Roland Wolf |
