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Anti-CD16 [3G8]

Info

Applications IHC IP
Antigen/Gene or Protein Targets CD16
Synonyms Fc Fragment Of IgG Receptor IIIa 2 3; Fc Fragment Of IgG; Low Affinity IIIa; Receptor (CD16a) 2 3 5; Fc Gamma Receptor IIIa 2 3; IgG Fc Receptor III-2 3 4; Fc-Gamma RIII-Alpha; CD16a Antigen; FCRIIIA; FCR-10; FCRIII; FCGR3; CD16A; IGFR3
Reactivity Human and Primate
Relevance 3G8 reacts to human CD16. CD16 is also known as low affinity IgG receptor III (FcyRIII) and is expressed as two distinct forms (CD16a and CD16b) CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and antibody-dependent cell-mediated cytotoxicity (ADCC).
Host Mouse
Immunogen Human PMN cells
Subclass IgG1 kappa
Positive Control Normal peripheral blood
Research Area Cell Type or Organelle Marker, Immunology, Stem Cell Biology

References: 2 entries

Romee et al. 2013. Blood. 121(18):3599-608. PMID: 23487023.

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).

Europe PMC ID: 23487023


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References: 2 entries

Romee et al. 2013. Blood. 121(18):3599-608. PMID: 23487023.

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).

Europe PMC ID: 23487023


Add a reference

References: 2 entries

Romee et al. 2013. Blood. 121(18):3599-608. PMID: 23487023.

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).


Add a reference


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