Anti-CD16 [3G8]
Invented at The Rockefeller University
- Datasheet
- References (2)
- Inventor Info
Info
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| Applications | IHC IP |
| Antigen/Gene or Protein Targets | CD16 |
| Synonyms | Fc Fragment Of IgG Receptor IIIa 2 3; Fc Fragment Of IgG; Low Affinity IIIa; Receptor (CD16a) 2 3 5; Fc Gamma Receptor IIIa 2 3; IgG Fc Receptor III-2 3 4; Fc-Gamma RIII-Alpha; CD16a Antigen; FCRIIIA; FCR-10; FCRIII; FCGR3; CD16A; IGFR3 |
| Reactivity | Human and Primate |
| Relevance | 3G8 reacts to human CD16. CD16 is also known as low affinity IgG receptor III (FcyRIII) and is expressed as two distinct forms (CD16a and CD16b) CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and antibody-dependent cell-mediated cytotoxicity (ADCC). |
| Host | Mouse |
| Immunogen | Human PMN cells |
| Positive Control | Normal peripheral blood |
| Subclass | IgG1 kappa |
| Research Area | Cell Type or Organelle Marker, Immunology, Stem Cell Biology |
References: 2 entries
Romee et al. 2013. Blood. 121(18):3599-608. PMID: 23487023.
NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).
Europe PMC ID: 23487023
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References: 2 entries
Romee et al. 2013. Blood. 121(18):3599-608. PMID: 23487023.
NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17).
Add a reference
