Anti-MSX1, Polyclonal [MSX1]
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Info
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | MSX1 |
| Reactivity | Human and Mouse |
| Relevance | Acts as a transcriptional repressor. May play a role in limbpattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity. This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limbpattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, WolfHirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq] |
| Host | Rabbit |
| Immunogen | 3 synthetic peptides (human) conjugated to KLH |
| Formulation | 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal. |
| Method of Purification | Immunogen affinity purification |
| Molecular Weight (kDa) | 30.9 |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Neurobiology |
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