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Anti-TFE3, Polyclonal [TFE3]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets TFE3
Reactivity Human and Mouse
Relevance Transcription factor that specifically recognizes and binds E-box sequences (5'- CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Formulation 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal.
Method of Purification Immunogen affinity purification
Molecular Weight (kDa) 61.5
Research Area Epigenetics & Nuclear Signalling, Immunology

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