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Anti-Proliferation marker [JC1]

Info

Catalogue Number 151401
Applications IHC IF WB
Antigen/Gene or Protein Targets Proliferation marker
Reactivity Human
Relevance JC1 detects a nuclear antigen, distinct from Ki67, present in proliferating cells. It is useful as a marker of proliferation in cases such as squamous cell carcinoma where the Ki67 index cannot be determined.
Host Mouse
Immunogen Pokeweed-stimulated lymphocytes
Subclass IgG2a
Molecular Weight (kDa) 212 and 123
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cancer, Cell Cycle, Cell Type or Organelle Marker, Neurobiology

References: 4 entries

Li et al. 2017. J Exp Clin Cancer Res. 36(1):58. PMID: 28427443.

Wang et al. 2016. Am J Cancer Res. 6(6):1331-44. PMID: 27429847.

Zhang et al. 2016. J Med Chem. 59(7):3562-8. PMID: 27006991.

Garrido et al. 1992. J Clin Pathol. 45(10):860-5. PMID: 1430255.


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