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Anti-ELK3, Polyclonal [ELK3]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets ELK3
Reactivity Human and Mouse
Relevance May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. The protein encoded by this gene is a member of the ETS­domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal­induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Molecular Weight (kDa) 44.2   
Research Area Epigenetics & Nuclear Signalling, Immunology

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