Anti-ELK3, Polyclonal [ELK3]
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Info
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | ELK3 |
| Reactivity | Human and Mouse |
| Relevance | May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. The protein encoded by this gene is a member of the ETSdomain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signalinduced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. |
| Host | Rabbit |
| Immunogen | 3 synthetic peptides (human) conjugated to KLH |
| Molecular Weight (kDa) | 44.2 |
| Research Area | Epigenetics & Nuclear Signalling, Immunology |
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