Anti-MHC-class I [YTH 862.2]
Invented by Herman Waldmann , Helen Tighe
Invented at University of Cambridge
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Info
| Applications | FACS IHC IP |
| Antigen/Gene or Protein Targets | MHC-class I |
| Reactivity | Human |
| Relevance | Class I MHC molecules are present as transmembrane glycoproteins on the surface of all nucleated cells. Intact class I molecules consist of an α heavy chain bound to a β 2 -microglobulin molecule. The heavy chain consists of 2 peptide-binding domains, an Ig-like domain, and a transmembrane region with a cytoplasmic tail. Clone YTH 862.2 recognizes a monomorphic determinant on the human MHC Class I heavy chain. |
| Host | Rat |
| Subclass | IgG2b |
| Research Area | Immunology |
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Inventor Information
Inventors
|
Herman Waldmann |
|
|
Helen Tighe |
