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Anti-MHC-class I [YTH 862.2]

Invented by Herman Waldmann, Helen Tighe

Info

Applications FACS IHC IP
Antigen/Gene or Protein Targets MHC-class I
Reactivity Human
Relevance Class I MHC molecules are present as transmembrane glycoproteins on the surface of all nucleated cells. Intact class I molecules consist of an α heavy chain bound to a β 2 -microglobulin molecule. The heavy chain consists of 2 peptide-binding domains, an Ig-like domain, and a transmembrane region with a cytoplasmic tail. Clone YTH 862.2 recognizes a monomorphic determinant on the human MHC Class I heavy chain.
Host Rat
Subclass IgG2b
Research Area Immunology

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