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Anti-PKCa [MC5]

Info

Catalogue Number 151131
Applications ELISA FACS IHC IF IP RIA WB
Antigen/Gene or Protein Targets Protein Kinase C alpha
Reactivity Bovine
Relevance Protein Kinase C is a family of serine/threonine protein kinases that are activated by Ca2+, diacylglycerol and membrane phospholipids (phosphatidylserine). MC5 blocks partial proteolysis of PKC by trypsin in vitro. Fab fragment inhibits phorbol-ester-induced down-regulation of PKC in a rodent gloma cell line.
Host Mouse
Immunogen Purified bovine brain protein kinase C
Subclass IgG2a
Molecular Weight (kDa) 80
Myeloma Used P3X63Ag8
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction

References: 3 entries

Kim et al. 2008. Nature. 452(7186):478-82. PMID: 18368118.

Ng et al. 1999. EMBO J. 18(14):3909-23. PMID: 10406796.

Young et al. 1988. Eur J Biochem. 173(1):247-52. PMID: 2451608.


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