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Anti-PKCa [MC5]

Info

Catalogue Number 151131
Applications ELISA FACS IHC IF IP RIA WB
Antigen/Gene or Protein Targets Protein Kinase C alpha
Reactivity Bovine
Relevance Protein Kinase C is a family of serine/threonine protein kinases that are activated by Ca2+, diacylglycerol and membrane phospholipids (phosphatidylserine). MC5 blocks partial proteolysis of PKC by trypsin in vitro. Fab fragment inhibits phorbol-ester-induced down-regulation of PKC in a rodent gloma cell line.
Host Mouse
Immunogen Purified bovine brain protein kinase C
Subclass IgG2a
Molecular Weight (kDa) 80
Myeloma Used P3X63Ag8
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction

References: 6 entries

Kim et al. 2008. Nature. 452(7186):478-82. PMID: 18368118.

Molecular identification of a retinal cell type that responds to upward motion.

Europe PMC ID: 18368118

Ng et al. 1999. EMBO J. 18(14):3909-23. PMID: 10406796.

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic.

Europe PMC ID: 10406796

Young et al. 1988. Eur J Biochem. 173(1):247-52. PMID: 2451608.

A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo.

Europe PMC ID: 2451608


Add a reference

References: 6 entries

Kim et al. 2008. Nature. 452(7186):478-82. PMID: 18368118.

Molecular identification of a retinal cell type that responds to upward motion.

Europe PMC ID: 18368118

Ng et al. 1999. EMBO J. 18(14):3909-23. PMID: 10406796.

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic.

Europe PMC ID: 10406796

Young et al. 1988. Eur J Biochem. 173(1):247-52. PMID: 2451608.

A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo.

Europe PMC ID: 2451608


Add a reference

References: 6 entries

Kim et al. 2008. Nature. 452(7186):478-82. PMID: 18368118.

Molecular identification of a retinal cell type that responds to upward motion.

Ng et al. 1999. EMBO J. 18(14):3909-23. PMID: 10406796.

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic.

Young et al. 1988. Eur J Biochem. 173(1):247-52. PMID: 2451608.

A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo.


Add a reference


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