Anti-HDAC1 [2E10]
Invented by Egon Ogris at Medical University Of Vienna
- Datasheet
- References (8)
- Inventor Info
Info
| Applications | IP WB |
| Antigen/Gene or Protein Targets | HDAC1 |
| Reactivity | Human and Mouse |
| Relevance | Histone deacetylase 1 is an nuclear enzyme encoded by the Hdac1 gene (also known as HD1, RPD3, MommeD5, Hdac1-ps) in mouse and HDAC1 (also known as GoON-10, RPD3L1) gene in human. Hdac1 plays an important role in epigenetic regulation of gene expression by catalyzing the hydrolysis of N(6)-acetylated histone lysine residues. Hdac1 is also known to deacetylate p53 and thereby downregulate p53 activity. |
| Host | Mouse |
| Immunogen | KLH-conjugated linear peptide corresponding to mouse HDAC1. |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 60 |
| Research Area | Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Stem Cell Biology |
References: 8 entries
Reichert et al. 2012. Radiother Oncol. 103(3):394-401. PMID: 22560712.
Keim et al. 2012. J Neurosci Methods. 206(2):138-42. PMID: 22387260.
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.
Europe PMC ID: 22560712
Negraes et al. 2012. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2D.9. PMID: 22415841.
El Ghazi et al. 2012. Neurobiol Dis. 45(3):871-86. PMID: 22209711.
Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.
Europe PMC ID: 22415841
Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer.
Europe PMC ID: 22387260
NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.
Europe PMC ID: 22209711
Add a reference
References: 8 entries
Reichert et al. 2012. Radiother Oncol. 103(3):394-401. PMID: 22560712.
Keim et al. 2012. J Neurosci Methods. 206(2):138-42. PMID: 22387260.
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.
Negraes et al. 2012. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2D.9. PMID: 22415841.
El Ghazi et al. 2012. Neurobiol Dis. 45(3):871-86. PMID: 22209711.
Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.
Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer.
NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.
Add a reference
