Cancer Research Technology
Log in Register
Menu

Anti-HDAC1 [2E10]

Invented by Egon Ogris at Medical University Of Vienna

Info

Applications IP WB
Antigen/Gene or Protein Targets HDAC1
Reactivity Human and Mouse
Relevance Histone deacetylase 1 is an nuclear enzyme encoded by the Hdac1 gene (also known as HD1, RPD3, MommeD5, Hdac1-ps) in mouse and HDAC1 (also known as GoON-10, RPD3L1) gene in human. Hdac1 plays an important role in epigenetic regulation of gene expression by catalyzing the hydrolysis of N(6)-acetylated histone lysine residues. Hdac1 is also known to deacetylate p53 and thereby downregulate p53 activity.
Host Mouse
Immunogen KLH-conjugated linear peptide corresponding to mouse HDAC1.
Subclass IgG1 kappa
Molecular Weight (kDa) 60
Research Area Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Stem Cell Biology

References: 8 entries

Reichert et al. 2012. Radiother Oncol. 103(3):394-401. PMID: 22560712.

Keim et al. 2012. J Neurosci Methods. 206(2):138-42. PMID: 22387260.

A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.

Europe PMC ID: 22560712

Negraes et al. 2012. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2D.9. PMID: 22415841.

El Ghazi et al. 2012. Neurobiol Dis. 45(3):871-86. PMID: 22209711.

Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.

Europe PMC ID: 22415841

Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer.

Europe PMC ID: 22387260

NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.

Europe PMC ID: 22209711


Add a reference

References: 8 entries

Reichert et al. 2012. Radiother Oncol. 103(3):394-401. PMID: 22560712.

Keim et al. 2012. J Neurosci Methods. 206(2):138-42. PMID: 22387260.

A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.

Europe PMC ID: 22560712

Negraes et al. 2012. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2D.9. PMID: 22415841.

El Ghazi et al. 2012. Neurobiol Dis. 45(3):871-86. PMID: 22209711.

Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.

Europe PMC ID: 22415841

Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer.

Europe PMC ID: 22387260

NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.

Europe PMC ID: 22209711


Add a reference

References: 8 entries

Reichert et al. 2012. Radiother Oncol. 103(3):394-401. PMID: 22560712.

Keim et al. 2012. J Neurosci Methods. 206(2):138-42. PMID: 22387260.

A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.

Negraes et al. 2012. Curr Protoc Stem Cell Biol. Chapter 2:Unit 2D.9. PMID: 22415841.

El Ghazi et al. 2012. Neurobiol Dis. 45(3):871-86. PMID: 22209711.

Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality.

Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer.

NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex.


Add a reference


This reagent does not have any reviews at the moment.