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PEO14 Cell Line

Invented by Simon Langdon at The University of Edinburgh

Info

Catalogue Number 151675
Host Human
Tissue Ovary
Disease Keywords Adenocarcinoma
Model Tumour line
Relevance The PEO14 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages) which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. PEO14 is an adherent cell line derived from a malignant effusion from the peritoneal ascites of a patient with a well differentiated serous adenocarcinoma. PEO14 was collected prior to treatment. PEO14 exhibits poor growth in semi-solid medium (agar). PEO14 is from the same patient as PEO16
Research Area Cancer, Drug Discovery & Development
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 104 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37°C. Doubling time approximately 108 hours.RPMI-1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum.
Cellosaurus ID CVCL_2687

References: 2 entries

Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.

Degos et al. 1979. Gastroenterol Clin Biol. 3(10):735-9. PMID: 316786.


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References: 2 entries

Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.

Degos et al. 1979. Gastroenterol Clin Biol. 3(10):735-9. PMID: 316786.


Add a reference

References: 2 entries

Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.

Degos et al. 1979. Gastroenterol Clin Biol. 3(10):735-9. PMID: 316786.


Add a reference


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