Anti-CCNH [33TF2-2D4]
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| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Cyclin H |
| Synonyms | Cyclin H; MO15-Associated Protein; Cyclin-Dependent Kinase-Activating; Kinase Complex Subunit; CDK-Activating Kinase Complex Subunit; CAK Complex Subunit; P34; P37; CycH; CAK |
| Reactivity | Human |
| Relevance | Monoclonal anti-Cyclin H antibody, clone 33TF2-2D4 has been validated for ELISA, Western Blot, Immunoprecipitation and Immunocytochemistry. Cyclin H belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. With its kinase partner, Cyclin H participates in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. |
| Host | Mouse |
| Immunogen | KKRKGYEDDDYVSKKSKHEE (Synthetic peptide corresponding to aa 292-311 (C-terminal region) of human cyclin H) |
| Subclass | IgG1 kappa |
| Notes |
Available in 100ul unit as ascites. Recommended dilutions: 1/500-1/5000 |
| Research Area | Cell Cycle, Epigenetics & Nuclear Signalling |
References: 2 entries
Adamczewski et al. 1996. EMBO J. 15(8):1877-84. PMID: 8617234.
MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH.
Europe PMC ID: 8617234
Add a reference
References: 2 entries
Adamczewski et al. 1996. EMBO J. 15(8):1877-84. PMID: 8617234.
MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH.
Europe PMC ID: 8617234
Add a reference
References: 2 entries
Adamczewski et al. 1996. EMBO J. 15(8):1877-84. PMID: 8617234.
MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH.
Add a reference
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