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Anti-EGFR [F4]

Info

Catalogue Number 151097
Applications ELISA FACS IHC IP RIA
Antigen/Gene or Protein Targets Epidermal Growth Factor Receptor (EGFR, Her1)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). Dysregulation of EGFR signaling as a consequence of overexpression, amplification and mutation of the EGFR gene occurs frequently in several types of cancers and many become dependent on EGFR signaling to maintain their malignant phenotypes.
Host Mouse
Immunogen Synthetic peptide (residues 985 to 996 of human EGFR) coupled to keyhole limpet hemocyanin.
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Signaling & Signal Transduction

References: 8 entries

Jaganathan et al. 2011. PLoS One. 6(5):e19605. PMID: 21573184.

A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Europe PMC ID: 21573184

Gibson et al. 2009. PLoS One. 4(9):e7222. PMID: 19787046.

Roles of specific membrane lipid domains in EGF receptor activation and cell adhesion molecule stabilization in a developing olfactory system.

Europe PMC ID: 19787046

Berger et al. 1987. J Pathol. 152(4):297-307. PMID: 3668732.

Epidermal growth factor receptors in lung tumours.

Europe PMC ID: 3668732

Gullick et al. 1986. Cancer Res. 46(1):285-92. PMID: 2998607.

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.

Europe PMC ID: 2998607


Add a reference

References: 8 entries

Jaganathan et al. 2011. PLoS One. 6(5):e19605. PMID: 21573184.

A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Europe PMC ID: 21573184

Gibson et al. 2009. PLoS One. 4(9):e7222. PMID: 19787046.

Roles of specific membrane lipid domains in EGF receptor activation and cell adhesion molecule stabilization in a developing olfactory system.

Europe PMC ID: 19787046

Berger et al. 1987. J Pathol. 152(4):297-307. PMID: 3668732.

Epidermal growth factor receptors in lung tumours.

Europe PMC ID: 3668732

Gullick et al. 1986. Cancer Res. 46(1):285-92. PMID: 2998607.

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.

Europe PMC ID: 2998607


Add a reference

References: 8 entries

Jaganathan et al. 2011. PLoS One. 6(5):e19605. PMID: 21573184.

A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Gibson et al. 2009. PLoS One. 4(9):e7222. PMID: 19787046.

Roles of specific membrane lipid domains in EGF receptor activation and cell adhesion molecule stabilization in a developing olfactory system.

Berger et al. 1987. J Pathol. 152(4):297-307. PMID: 3668732.

Epidermal growth factor receptors in lung tumours.

Gullick et al. 1986. Cancer Res. 46(1):285-92. PMID: 2998607.

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.


Add a reference


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