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(S248F) knock-in mice

Info

Antigen/Gene or Protein Targets S248F
Disease Keywords Dystonia
Model Knock-In
Relevance This mouse line has a missense mutation (S248F) in the gene (CHRNA4) encoding the α4 subunit of neuronal nicotinic acetylcholine receptor (nAChR). Mutant mice demonstrate brief nicotine induced dystonia that resembles the clinical events seen in patients with the same mutation. PMID: 19404753.
Strain CD1
Research Area Other

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References: 1 entry

Cannata et al. 2009. J Muscle Res Cell Motil. 30(1-2):73-83. PMID: 19404753.


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References: 1 entry

Cannata et al. 2009. J Muscle Res Cell Motil. 30(1-2):73-83. PMID: 19404753.


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