Anti-HIF1A [Ha111a]
Invented by Helen Turley from University of Oxford
Invented at University of Oxford
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151198 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Hypoxia-inducible factor 1, alpha subunit (HIF1A) |
| Reactivity | Human |
| Relevance | Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF1A has been observed in varying subsets of tumour cells from various solid tumours. |
| Host | Mouse |
| Immunogen | GST-human HIF1A amino acids 329-530 fusion protein |
| Subclass | IgG2a |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Research Area | Cancer, Epigenetics & Nuclear Signalling |
References: 4 entries
André et al. 2008. J Biol Chem. 283(43):29375-84. PMID: 18694926.
Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
Europe PMC ID: 18694926
Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.
Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
Europe PMC ID: 9746763
Add a reference
References: 4 entries
André et al. 2008. J Biol Chem. 283(43):29375-84. PMID: 18694926.
Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.
Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
Add a reference
