Anti-ORC1 [TK 1/2]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151195 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | ORC1 |
| Reactivity | Xenopus laevis |
| Relevance | DNA replication in S. cerevisiae requires the action of a multisubunit complex of six proteins known as the origin recognition complex (ORC). The identification of higher eukaryotic homologs of several ORC components suggests a universal role for this complex in DNA replication. |
| Host | Mouse |
| Immunogen | Full length ORC1 protein - Xenopus laevis |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | TK 1/2 does not recognise ORC1 protein from other species. |
| Research Area | Epigenetics & Nuclear Signalling |
References: 2 entries
Tugal et al. 1998. J Biol Chem. 273(49):32421-9. PMID: 9829972.
The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p.
Europe PMC ID: 9829972
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References: 2 entries
Tugal et al. 1998. J Biol Chem. 273(49):32421-9. PMID: 9829972.
The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p.
Add a reference
