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Anti-Rad51 [Rad51 3C10]

Invented by Dr Stephen West at Francis Crick Institute

Info

Catalogue Number 151196
Applications IHC IP WB
Antigen/Gene or Protein Targets Rad51
Reactivity Bovine, Human and Pig
Relevance RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination.
Host Mouse
Immunogen Full length recombinant human RAD51 protein
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 6 entries

Ivanov et al. 2003. J Cell Sci. 116(Pt 20):4095-106. PMID: 12953071.

Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks.

Europe PMC ID: 12953071

Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.

Europe PMC ID: 10562567

Barlow et al. 1997. EMBO J. 16(17):5207-15. PMID: 9311981.

Distribution of the Rad51 recombinase in human and mouse spermatocytes.

Europe PMC ID: 9311981


Add a reference

References: 6 entries

Ivanov et al. 2003. J Cell Sci. 116(Pt 20):4095-106. PMID: 12953071.

Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks.

Europe PMC ID: 12953071

Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.

Europe PMC ID: 10562567

Barlow et al. 1997. EMBO J. 16(17):5207-15. PMID: 9311981.

Distribution of the Rad51 recombinase in human and mouse spermatocytes.

Europe PMC ID: 9311981


Add a reference

References: 6 entries

Ivanov et al. 2003. J Cell Sci. 116(Pt 20):4095-106. PMID: 12953071.

Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks.

Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.

Barlow et al. 1997. EMBO J. 16(17):5207-15. PMID: 9311981.

Distribution of the Rad51 recombinase in human and mouse spermatocytes.


Add a reference


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