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HtrA3 Monoclonal Antibody (Clone 9C9)

Invented at Hudson Institute Of Medical Research

Info

Catalogue Number 154233
Applications ELISA
Antigen/Gene or Protein Targets Human HtrA3 (high temperature requirement factor A)
Synonyms HtrA3
Reactivity Human
Relevance Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Host Mouse
Immunogen HtrA3-L-S305A protein
Immunogen UniProt ID P83110, HTRA3_HUMAN
Molecular Weight (kDa) 48 kDa (46.9 kDa plus 1 kDa for the His tag)
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions Sp2/0 myeloma cells in the presence of 50% (w/v) polyethylene glycol 1500. Cells resuspendedin Hybridoma Serum Free Medium (Invitrogen), supplemented with 10% (w/v) FCS, HAT medium (Invitrogen) and IL-6 (1:1000 dilution).
Strain Balb/c
Notes Used in combination with Clone 6G6 for detection of long-isoform of HtrA3 (human studies)
Research Area Gynaecaology, Reproductive Biology

References

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References: 3 entries

23049902

25248123

27932697


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References: 3 entries

23049902

25248123

27932697


Add a reference

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