HtrA3 Monoclonal Antibody (Clone 9C9)

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References (3)

Inventor Info

Info

Catalogue Number	154233
Applications	ELISA
Antigen/Gene or Protein Targets	Human HtrA3 (high temperature requirement factor A)
Synonyms	HtrA3
Reactivity	Human
Relevance	Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Host	Mouse
Immunogen	HtrA3-L-S305A protein
Immunogen UniProt ID	P83110, HTRA3_HUMAN
Molecular Weight (kDa)	48 kDa (46.9 kDa plus 1 kDa for the His tag)
Myeloma Used	Sp2/0-Ag14
Recommended Growing Conditions	Sp2/0 myeloma cells in the presence of 50% (w/v) polyethylene glycol 1500. Cells resuspendedin Hybridoma Serum Free Medium (Invitrogen), supplemented with 10% (w/v) FCS, HAT medium (Invitrogen) and IL-6 (1:1000 dilution).
Strain	Balb/c
Notes	Used in combination with Clone 6G6 for detection of long-isoform of HtrA3 (human studies)
Research Area	Gynaecaology, Reproductive Biology

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23049902

25248123

27932697

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23049902

25248123

27932697

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	Hudson Institute Of Medical Research
	16 reagents listed on Ximbio

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