T10 SCC Cell Line
Invented by Prof Irene Leigh from Queen Mary University of London
Invented at Queen Mary University of London
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153674 |
| Antigen/Gene or Protein Targets | Squamous Cell Carcinoma |
| Synonyms | SCC, Squamous cell carcinoma, T10 |
| Host | Human |
| Disease Keywords | Cancer, Skin Cancer, Squamous Cell Carcinoma |
| Model | Tumour line |
| Relevance | The SCC series represent primary, recurrent and metastatic carcinoma. Availability of such a series from the same individual will facilitate genetic analysis of the malignant process. |
| Production Details | Cutaneous SCC cell line from 60 year old male. Moderately defined primary tumour from the left shin with germline DNA from lymphocytes. Patient had a renal transplant and was treated with Azathioprine (A), Mycophenolate mofetil (MMF), Cyclosporine and Prednisolone. At time of lesional biopsy the patient had stopped receiving treatment of A and MMF. |
| Research Area | Cancer |
| Recommended Growing Conditions | Keratinocyte cell culture media supplemented with 10ng/ml EGF |
References: 2 entries
Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.
Europe PMC ID: 30202019
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References: 2 entries
Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.
Add a reference
