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T10 SCC Cell Line

Info

Catalogue Number 153674
Antigen/Gene or Protein Targets Squamous Cell Carcinoma
Synonyms SCC, Squamous cell carcinoma, T10
Host Human
Disease Keywords Cancer, Skin Cancer, Squamous Cell Carcinoma
Model Tumour line
Relevance The SCC series represent primary, recurrent and metastatic carcinoma. Availability of such a series from the same individual will facilitate genetic analysis of the malignant process.
Production Details Cutaneous SCC cell line from 60 year old male. Moderately defined primary tumour from the left shin with germline DNA from lymphocytes. Patient had a renal transplant and was treated with Azathioprine (A), Mycophenolate mofetil (MMF), Cyclosporine and Prednisolone. At time of lesional biopsy the patient had stopped receiving treatment of A and MMF.
Research Area Cancer
Recommended Growing Conditions Keratinocyte cell culture media supplemented with 10ng/ml EGF

References

There are 2 reference entries for this reagent.

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References: 2 entries

Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.

Europe PMC ID: 30202019


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References: 2 entries

Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.


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