Anti-CD9 [BU16]
Invented at University Of Birmingham
Anti-CD9 [P1/33/2]
Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 151347 |
| Applications | FACS IHC |
| Antigen/Gene or Protein Targets | CD9 |
| Synonyms | CD9 Molecule; Cell Growth-Inhibiting Gene 2 Protein; Motility Related Protein-1; Leukocyte Antigen MIC3; CD9 Antigen (P24); Tetraspanin-29; 5H9 Antigen; TSPAN29; MRP-1 |
| Reactivity | Human |
| Relevance | CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FcgRIIa. It may play a role in cell migration.Antibodies against CD9 have utility in characterisation of acute leukaemias and in some cases AML and for functional studies on platelets |
| Host | Mouse |
| Immunogen | Acute lymphoblastic leukaemia cells |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cancer, Cardiovascular, Cell Type or Organelle Marker, Developmental Biology, Immunology, Stem Cell Biology |
References: 3 entries
Taghizadeh et al. 2010. PLoS One. 5(12):e15183. PMID: 21203549.
IHC
CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.
Europe PMC ID: 21203549
Jennings et al. 1993. CD9 cluster workshop report: cell surface binding and functional analysis. In Schlossman SF, et al (eds) Leucocyte Typing V, Vol 2, Oxford University Press, Oxford, New York and Tokyo, p 1249-51
Add a reference
References: 3 entries
Taghizadeh et al. 2010. PLoS One. 5(12):e15183. PMID: 21203549.
IHC
CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.
Jennings et al. 1993. CD9 cluster workshop report: cell surface binding and functional analysis. In Schlossman SF, et al (eds) Leucocyte Typing V, Vol 2, Oxford University Press, Oxford, New York and Tokyo, p 1249-51
Add a reference
