Anti-FCGR2 [2ZC115]
Invented by Karen Pulford from University of Oxford
Invented at University of Oxford
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151358 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | Fc gamma Recptor II (FCGR2, CD32) |
| Synonyms | Fc Fragment Of IgG Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2; FCG2; CD32; FCGR2; CD32B |
| Reactivity | Human |
| Relevance | Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils. |
| Host | Mouse |
| Immunogen | Hairy cell leukaemia cells |
| Subclass | IgG2a |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Immunology, Stem Cell Biology |
References: 4 entries
Greenman et al. 1991. Mol Immunol. 28(11):1243-54. PMID: 1835758.
Characterization of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors.
Europe PMC ID: 1835758
Pulford et al. 1986. Immunology. 57(1):71-6. PMID: 3484721.
A new monoclonal antibody (KB61) recognizing a novel antigen which is selectively expressed on a subpopulation of human B lymphocytes.
Europe PMC ID: 3484721
Add a reference
References: 4 entries
Greenman et al. 1991. Mol Immunol. 28(11):1243-54. PMID: 1835758.
Characterization of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors.
Pulford et al. 1986. Immunology. 57(1):71-6. PMID: 3484721.
A new monoclonal antibody (KB61) recognizing a novel antigen which is selectively expressed on a subpopulation of human B lymphocytes.
Add a reference
