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Anti-HA (H1N1) [LM41] monoclonal antibody

Invented by Nigel Dimmock at University Of Warwick

Info

Catalogue Number 153417
Applications ELISA Fn
Antigen/Gene or Protein Targets A/WSN (H1N1) hemagglutinin
Synonyms Hemagglutinin Antibody, Anti-HA, HA, Antibody, Anti-Influenza A, Anti-H1N1 HA, Influenza A Antibody, Flu Antibody, AWSN Antibody, H1N1 Antibody, Anti-AWSN, A/WSN Antibody, Anti-A/WSN
Reactivity Virus
Relevance The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice.
Host Mouse
Immunogen C3WHe-mg (H-2k) mice were infected with A/WSN (H1N1)
Subclass IgM
Myeloma Used Sp2/0-Ag14
Research Area Immunology, Virology

References

There are 1 reference entries for this reagent.

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References: 1 entry

McLain et al. 1993. J Immunol. 150(8 Pt 1):3421-6. PMID: 7682240.


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References: 1 entry

McLain et al. 1993. J Immunol. 150(8 Pt 1):3421-6. PMID: 7682240.


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Inventor Information