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Anti-CD72 [BU40]


Catalogue Number 151433
Applications FACS IHC IP WB
Antigen/Gene or Protein Targets CD72
Synonyms CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
Reactivity Human
Relevance CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
Host Mouse
Immunogen HF B1 plasmacytoid cell line. Considered to be “late B like”.
Subclass IgG2a
Recommended Growing Conditions RPMI 1640 + 10% FCS
Notes Flow Cytometry: 1:50 - 1:100.

Immunohistochemistry on paraffin sections: 1:50; This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.

Immunoprecipitation 1:10-1:500

Western Blot 1:100-1:2000

Immunohistochemistry 1:10-1:2000

Immunohistochemistry-Frozen 1:10-1:2000
Research Area Immunology, Stem Cell Biology

References: 4 entries

Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672

Ishida et al. 2003. Int Immunol. 15(8):1027-34. PMID: 12882840.

Schwarting et al. 1992. Am J Hematol. 41(3):151-8. PMID: 1384316.

Van de Velde et al. 1991. Nature. 351(6328):662-5. PMID: 1711157.

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