Anti-CD72 [BU40]
Invented at University Of Birmingham
- Datasheet
- References (7)
- Inventor Info
Info
| Catalogue Number | 151433 |
| Applications | FACS IHC IP WB |
| Antigen/Gene or Protein Targets | CD72 |
| Synonyms | CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2 |
| Reactivity | Human |
| Relevance | CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation. |
| Host | Mouse |
| Immunogen | HF B1 plasmacytoid cell line. Considered to be “late B like”. |
| Subclass | IgG2a |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Notes |
Flow Cytometry: 1:50 - 1:100. Immunohistochemistry on paraffin sections: 1:50; This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase. Immunoprecipitation 1:10-1:500 Western Blot 1:100-1:2000 Immunohistochemistry 1:10-1:2000 Immunohistochemistry-Frozen 1:10-1:2000 |
| Research Area | Immunology, Stem Cell Biology |
References: 7 entries
Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672
Ishida et al. 2003. Int Immunol. 15(8):1027-34. PMID: 12882840.
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses.
Europe PMC ID: 12882840
Schwarting et al. 1992. Am J Hematol. 41(3):151-8. PMID: 1384316.
Human Lyb-2 homolog CD72 is a marker for progenitor B-cell leukemias.
Europe PMC ID: 1384316
Van de Velde et al. 1991. Nature. 351(6328):662-5. PMID: 1711157.
The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.
Europe PMC ID: 1711157
Add a reference
References: 7 entries
Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672
Ishida et al. 2003. Int Immunol. 15(8):1027-34. PMID: 12882840.
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses.
Schwarting et al. 1992. Am J Hematol. 41(3):151-8. PMID: 1384316.
Human Lyb-2 homolog CD72 is a marker for progenitor B-cell leukemias.
Van de Velde et al. 1991. Nature. 351(6328):662-5. PMID: 1711157.
The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.
Add a reference
