Anti-CD70 [BU69]
Invented at University Of Birmingham
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 151436 |
| Applications | FACS IHC IP |
| Antigen/Gene or Protein Targets | CD70 |
| Synonyms | CD70 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A |
| Reactivity | Human |
| Relevance | CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells. |
| Host | Mouse |
| Immunogen | Waldenstroms macroglobulineamia cell line WM-1 |
| Positive Control | Raji cells |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 30 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS |
| Strain | Balb/c |
| Notes | BU69 inhibits T cell proliferation induced by dendritic cells. |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Immunology, Stem Cell Biology |
References: 3 entries
Schlossman, S.F. et al. 1995 Leukocyte Typing V Oxford University Press
Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.
A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells.
Europe PMC ID: 10415041
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References: 3 entries
Schlossman, S.F. et al. 1995 Leukocyte Typing V Oxford University Press
Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.
A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells.
Add a reference
