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Anti-CD70 [BU69]


Catalogue Number 151436
Applications FACS IHC IP
Antigen/Gene or Protein Targets CD70
Synonyms CD70 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A
Reactivity Human
Relevance CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells.
Host Mouse
Immunogen Waldenstroms macroglobulineamia cell line WM-1
Subclass IgG1
Positive Control Raji cells
Molecular Weight (kDa) 30
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS
Strain Balb/c
Notes BU69 inhibits T cell proliferation induced by dendritic cells.
Research Area Apoptosis and Programmed Cell Death, Cancer, Immunology, Stem Cell Biology

References: 2 entries

Schlossman, S.F. et al. 1995 Leukocyte Typing V Oxford University Press

Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.

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