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Catalogue Number 152849
Host Human
Tissue Alveolus
Disease Keywords Oral alveolus squamous carcinoma
Model Tumour line
Relevance Adherent keratinocyte cell line derived from a squamous cell carcinoma of the oral alveolus of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are not tumourigenic in athymic mice.
Research Area
RECENTLY UPDATED
Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
Cellosaurus ID CVCL_2315

References

There are 2 reference entries for this reagent.

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References: 2 entries
RECENTLY UPDATED

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

Europe PMC ID: 7646764


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References: 2 entries
RECENTLY UPDATED

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.


Add a reference