BICR 78 Cell Line
Invented by Prof Eric Kenneth Parkinson from Queen Mary University of London
Invented at Cancer Research UK Glasgow: The Beatson Institute
- Datasheet
- References (2)
- Inventor Info
Info
Catalogue Number | 152849 |
Host | Human |
Tissue | Alveolus |
Disease Keywords | Oral alveolus squamous carcinoma |
Model | Tumour line |
Relevance | Adherent keratinocyte cell line derived from a squamous cell carcinoma of the oral alveolus of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are not tumourigenic in athymic mice. |
Research Area | Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling |
Growth/Phenotype Keywords | Adherent |
Recommended Growing Conditions | DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone. |
Cellosaurus ID | CVCL_2315 |
References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Europe PMC ID: 7646764
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References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Add a reference