BICR 10 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 18 Cell Line
Invented by Prof Eric Kenneth Parkinson from Queen Mary University of London
Invented at Cancer Research UK Glasgow: The Beatson Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 152843 |
| Host | Human |
| Tissue | Larynx |
| Disease Keywords | Larynx squamous cell carcinoma (lymph node metastasis) |
| Model | Tumour line |
| Relevance | Adherent keratinocyte cell line derived from a lymph node metastasis squamous cell carcinoma (SSC) of the larynx. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. By short tandem repeat (STR)-PCR analysis the Y chromosome could not be detected in this cell line. It is a known phenomenon that SSC cell lines can lose their Y chromosome. |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling |
| Growth/Phenotype Keywords | Adherent |
| Recommended Growing Conditions | DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone. |
| Notes |
STR-PCR Data: Amelogenin: X CSF1PO: 11,12 D13S317: 8,13 D16S539: 12,14 D5S818: 12 D7S820: 9 THO1: 7 TPOX: 9,12 vWA: 17,20 |
| Cellosaurus ID | CVCL_2309 |
BICR 16 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 3 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 56 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 6 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 78 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 22 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 31 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
BICR 82 Cell Line
Invented by Prof Eric Kenneth Parkinson at Cancer Research UK Glasgow: The Beatson Institute
References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Europe PMC ID: 7646764
Add a reference
References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Add a reference
