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Catalogue Number 152848
Host Human
Tissue Hypopharynx
Disease Keywords Hypopharynx squamous cell carcinoma
Model Tumour line
Relevance Adherent keratinocyte cell line derived from a squamous cell carcinoma of the hypopharynx of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present.
Research Area
RECENTLY UPDATED
Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
Notes STR-PCR Data:
Amelogenin: X, Y
CSF1PO: 10
D13S317: 14
D16S539: 11
D5S818: 12
D7S820: 10
THO1: 6
TPOX: 9,11
vWA: 16,17
Cellosaurus ID CVCL_2314

References

There are 2 reference entries for this reagent.

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References: 2 entries
RECENTLY UPDATED

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

Europe PMC ID: 7646764


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References: 2 entries
RECENTLY UPDATED

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.


Add a reference