Cancer Research Technology
Log in Register
Menu

Info

Catalogue Number 152848
Host Human
Tissue Hypopharynx
Disease Keywords Hypopharynx squamous cell carcinoma
Model Tumour line
Relevance Adherent keratinocyte cell line derived from a squamous cell carcinoma of the hypopharynx of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present.
Research Area Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
Notes STR-PCR Data:
Amelogenin: X, Y
CSF1PO: 10
D13S317: 14
D16S539: 11
D5S818: 12
D7S820: 10
THO1: 6
TPOX: 9,11
vWA: 16,17
Cellosaurus ID CVCL_2314

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

Europe PMC ID: 7646764


Add a reference

References: 2 entries

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.


Add a reference