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Cell Lines

BICR 56 Cell Line

Invented by Prof Eric Kenneth Parkinson from Queen Mary University of London
Invented at Cancer Research UK Glasgow: The Beatson Institute
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BICR 56 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)
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Catalogue Number 152847
Host Human
Tissue Tongue
Disease Keywords Tongue squamous carcinoma
Model Tumour line
Relevance Adherent keratinocyte cell line derived from a squamous cell carcinoma of the tongue of a Caucasian female. Keratin and involucrin markers present. Known mutations: p53 and p16. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present.
Research Area Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
Notes STR-PCR Data:
Amelogenin: X
CSF1PO: 12
D13S317: 12
D16S539: 11
D5S818: 11,12
D7S820: 8,12
THO1: 9,9.3
TPOX: 8,9
vWA: 15,16
Cellosaurus ID CVCL_2313

References

There are 2 reference entries for this reagent.

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References: 2 entries

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

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Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

Europe PMC ID: 7646764

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References: 2 entries

Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.

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Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

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Inventor Information