BICR 16 Cell Line
Invented by Prof Eric Kenneth Parkinson from Queen Mary University of London
Invented at Cancer Research UK Glasgow: The Beatson Institute
- Datasheet
- References (2)
- Inventor Info
Info
Catalogue Number | 152842 |
Host | Human |
Tissue | Tongue |
Disease Keywords | Buccal mucosa squamous carcinoma |
Model | Tumour line |
Relevance | Adherent cell line derived from a recurrent squamous cell carcinoma of the tongue of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. |
Research Area | Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling |
Growth/Phenotype Keywords | Adherent |
Recommended Growing Conditions | DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone. |
Notes |
STR-PCR Data: Amelogenin: X, X CSF1PO: 12 D13S317: 11 D16S539: 12 D5S818: 13 D7S820: 10 THO1: 6,9 TPOX: 8,11 vWA: 17,19 |
Cellosaurus ID | CVCL_2308 |
References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Europe PMC ID: 7646764
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References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Add a reference