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Catalogue Number 152414
Applications IP WB
Antigen/Gene or Protein Targets Human papillomavirus type 18 (HPV18) E6 protein
Reactivity Human papilloma virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
Host Mouse
Immunogen HPV-18 E6-beta-galactosidase fusion protein
Subclass IgG3
Myeloma Used P3/NS1/1-Ag4.1
Research Area Cancer, Virology

References: 1 entry

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

IP WB


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References: 1 entry

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

IP WB


Add a reference

References: 1 entry

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

IP WB


Add a reference


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