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Anti-Trim28 [1Tb-1A9]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  TIF1 Beta 
Synonyms Trim28, KAP1
Reactivity N/A
Relevance Tripartite motif-containing 28 (Trim28) also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1) is a member of the tripartite motif family, which localizes to the nucleus and is thought to associate with specific chromatin regions. Trim28 has been reported to function as a co-repressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins. As such, it plays a crucial role in early embryogenesis. It appears that the co-repressor function of TIF1 beta is related to its organization and/or maintenance of higher-order, heterochromatin-like structures.
Host Mouse
Immunogen Recomb prot
Subclass IgG2b kappa
Notes Available in 100ul unit
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Protein Degradation, Stem Cell Biology

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