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Anti-RARB [8β-10B2]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  RAR Beta  
Reactivity Human and Mouse
Relevance Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Host Mouse
Immunogen Recombinant protein (413-448)
Notes Available in 100ul unit. No cross reactivity on RARa and RARg.
Research Area Epigenetics & Nuclear Signalling

References: 1 entry

Rochette-Egly et al. 1992. Mol Endocrinol. 6(12):2197-209. PMID: 1283441.


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References: 1 entry

Rochette-Egly et al. 1992. Mol Endocrinol. 6(12):2197-209. PMID: 1283441.


Add a reference

References: 1 entry

Rochette-Egly et al. 1992. Mol Endocrinol. 6(12):2197-209. PMID: 1283441.


Add a reference


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