Anti-Kidins220 [p220 1F8/3]
Invented by Giampietro Schiavo from University College London
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151252 |
| Applications | ELISA IHC IP WB |
| Antigen/Gene or Protein Targets | Kidins220/ARMS |
| Reactivity | Rat |
| Relevance | Kidins220/ARMS (Kinase D-Interacting Substrate of 220 kDa, ARMS; Ankyrin Repeat-rich Membrane Spanning) is an integral membrane protein that is selectively expressed in brain and neuroendocrine cells and phosphorylated by PKD (protein Kinase D). Kidins220 has also been shown to function downstream of the Trk and Eph receptor tyrosine kinases. |
| Host | Mouse |
| Immunogen | Recombinant GST-Kidins220/ARMS (last 347 amino acids at the carboxy terminus) fusion protein. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 220 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cardiovascular, Cell Signaling & Signal Transduction, Neurobiology |
References: 6 entries
Deswal et al. 2013. J Immunol. 190(5):1927-35. PMID: 23359496.
Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells.
Europe PMC ID: 23359496
Bracale et al. 2007. Mol Biol Cell. 18(1):142-52. PMID: 17079733.
Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation.
Europe PMC ID: 17079733
Iglesias et al. 2000. J Biol Chem. 275(51):40048-56. PMID: 10998417.
Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D.
Europe PMC ID: 10998417
Add a reference
References: 6 entries
Deswal et al. 2013. J Immunol. 190(5):1927-35. PMID: 23359496.
Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells.
Bracale et al. 2007. Mol Biol Cell. 18(1):142-52. PMID: 17079733.
Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation.
Iglesias et al. 2000. J Biol Chem. 275(51):40048-56. PMID: 10998417.
Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D.
Add a reference
