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Anti-HIF1A [Hif28b]

Invented by Helen Turley at University of Oxford

Info

Catalogue Number 151259
Applications ELISA IHC
Antigen/Gene or Protein Targets Hypoxia-inducible factor 1, alpha subunit (HIF1A)
Reactivity Human
Relevance Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF1A has been observed in varying subsets of tumour cells from various solid tumours.
Host Mouse
Immunogen Immunogen containing human HIF1A amino acids 329-530.
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions E4 + 10% FCS + HAT
Strain Balb/c
Research Area Cancer, Epigenetics & Nuclear Signalling

References: 10 entries

Giatromanolaki et al. 2003. J Pathol. 200(2):222-8. PMID: 12754744.

DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.

Europe PMC ID: 12754744

Hui et al. 2002. Clin Cancer Res. 8(8):2595-604. PMID: 12171890.

Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

Europe PMC ID: 12171890

Beasley et al. 2002. Cancer Res. 62(9):2493-7. PMID: 11980639.

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients.

Europe PMC ID: 11980639

Talks et al. 2000. Am J Pathol. 157(2):411-21. PMID: 10934146.

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.

Europe PMC ID: 10934146

Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

Europe PMC ID: 9746763


Add a reference

References: 10 entries

Giatromanolaki et al. 2003. J Pathol. 200(2):222-8. PMID: 12754744.

DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.

Europe PMC ID: 12754744

Hui et al. 2002. Clin Cancer Res. 8(8):2595-604. PMID: 12171890.

Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

Europe PMC ID: 12171890

Beasley et al. 2002. Cancer Res. 62(9):2493-7. PMID: 11980639.

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients.

Europe PMC ID: 11980639

Talks et al. 2000. Am J Pathol. 157(2):411-21. PMID: 10934146.

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.

Europe PMC ID: 10934146

Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

Europe PMC ID: 9746763


Add a reference

References: 10 entries

Giatromanolaki et al. 2003. J Pathol. 200(2):222-8. PMID: 12754744.

DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.

Hui et al. 2002. Clin Cancer Res. 8(8):2595-604. PMID: 12171890.

Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

Beasley et al. 2002. Cancer Res. 62(9):2493-7. PMID: 11980639.

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients.

Talks et al. 2000. Am J Pathol. 157(2):411-21. PMID: 10934146.

The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.

Wiesener et al. 1998. Blood. 92(7):2260-8. PMID: 9746763.

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.


Add a reference


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