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Anti-MNAT1 [35TF2-2D3]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  MAT1-p32 / MNAT1 
Reactivity Human
Relevance The protein named Arylamine N-acetyltransferase 1 or alternatively Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase (MNAT), or N-acetyltransferase type 1 (NAT-1) is a detoxifying enzyme that helps to metabolize drugs and other xenobiotics. NAT1 also functions in folate catabolism. Interestingly, NAT1 is one of two N-acetyltransferase isozymes in humans that also catalyze both N-acetylation (usually deactivation) and O-acetylation (usually activation) of aromatic and heterocyclic amine carcinogens. Epidemiological studies suggest that the NAT1 and NAT2 acetylation polymorphisms modify risk of developing urinary bladder, colorectal, breast, head and neck, lung, and possibly prostate cancers. NAT1 is expressed principally in the liver but can also be found expressed in kidney, lung and trachea, with minor expression seen in most other tissues as well.
Host Mouse
Immunogen ALQDAFSGLFWQP
Subclass IgG1 kappa
Notes Available in 100ul unit
Research Area Cell Cycle, Epigenetics & Nuclear Signalling

References: 2 entries

Busso et al. 2000. J Biol Chem. 275(30):22815-23. PMID: 10801852.

Andersen et al. 1997. EMBO J. 16(5):958-67. PMID: 9118957.


Add a reference

References: 2 entries

Busso et al. 2000. J Biol Chem. 275(30):22815-23. PMID: 10801852.

Andersen et al. 1997. EMBO J. 16(5):958-67. PMID: 9118957.


Add a reference

References: 2 entries

Busso et al. 2000. J Biol Chem. 275(30):22815-23. PMID: 10801852.

Andersen et al. 1997. EMBO J. 16(5):958-67. PMID: 9118957.


Add a reference


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