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CLEC2 Floxed KO Mouse

Info

Catalogue Number 152150
Antigen/Gene or Protein Targets CLEC2
Disease Keywords Platelet aggregation
Relevance A novel mutant mouse that lacks functional CLEC2 and has been used to investigate the role of CLEC2 in platelet aggregation and thrombus formation. Enables removal of C-type lectin-like receptor type 2 from pertinent cell types when crossed with Cre-recominase expressing mice.
Conditional Yes
Conditional Description Conditional deletion of CLEC2 was achieved by insertion of loxP sites flanking exons 3 and 4 of the Clec1b gene
Mouse Genetic Background/Cross History Mice were bred as heterozygotes on a mixed C57B1/6 x 129Sv background
Zygosity Clec1b -/-
Research Area Genetic Studies Tools, Immunology

References: 2 entries

Finney et al. 2012. Blood. 119(7):1747-56. PMID: 22186994.

Hughes et al. 2010. J Thromb Haemost. 8(10):2328-32. PMID: 20695981.


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References: 2 entries

Finney et al. 2012. Blood. 119(7):1747-56. PMID: 22186994.

Hughes et al. 2010. J Thromb Haemost. 8(10):2328-32. PMID: 20695981.


Add a reference

References: 2 entries

Finney et al. 2012. Blood. 119(7):1747-56. PMID: 22186994.

Hughes et al. 2010. J Thromb Haemost. 8(10):2328-32. PMID: 20695981.


Add a reference


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