Anti-PP2R5E-B56 epsilon [5A5-1F3]
Invented by Egon Ogris at Medical University Of Vienna
- Datasheet
- References (0)
- Inventor Info
Info
Applications | IHC IP WB |
Antigen/Gene or Protein Targets | PP2A B56 epsilon |
Reactivity | Human |
Relevance | Protein phosphatase 2A (PP2A) is one of the most abundantly expressed serine/threonine protein phosphatases. A large body of evidence suggests that PP2A is a tumor suppressor and plays critical roles in regulating apoptosis. PP2A is a heterotrimeric protein complex. Its substrate specificity, localization, and activity are regulated by regulatory subunits of PP2A. A recent study has demonstrated that single nucleotide polymorphism in B56ε (PPP2R5E), a B56 family regulatory subunit of PP2A, is associated with human soft tissue sarcoma. This raises the possibility that B56ε is involved in tumorigenesis and plays important roles in regulating apoptosis. |
Host | Mouse |
Immunogen | Human B56 epsilon residues 2-126 |
Molecular Weight (kDa) | 54.7 |
Research Area | Apoptosis and Programmed Cell Death, Cancer |
References
There are 0 reference entries for this reagent.
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference