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Anti-mEMILIN1 [mEMIL] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
Anti-hEMILIN2 [hEMIL2] monoclonal antibody
Invented by Professor Alfonso Colombatti , Dr Maurizio Mongiat from National Cancer Institute CRO - Aviano , Dr Roberto Doliana , Maria Teresa Mucignat
Invented at National Cancer Institute CRO - Aviano
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 160587 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | hEMILIN2 |
| Reactivity | Human |
| Relevance | Emilin-2 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is involved in regulation of the extrinsic apoptotic pathway, by interacting with death receptors DR4 and DR5 and down-modulates the Wnt signalling pathway. EMILIN2 is also involved in the regulation of angiogenesis and elastogenesis |
| Host | Mouse |
| Immunogen | Recombinant human Emilin-2 as immunizing antigen; BALB/c mice as host |
| Positive Control | IgG2b kappa |
| Notes |
Storage Conditions Store at 2-8°C or aliquots at -20°C. Avoid repeated freeze-thaw cycles. Concentration Western Blot use at 2-5 μg/ml |
| Research Area | Cancer |
Anti-hEMILIN1 [hEMIL1] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
Anti-mMMRN2 [mMMRN2] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
References: 3 entries
Marastoni et al. 2014. J Pathol. 232(4):391-404. PMID: 24374807.
Mongiat et al. 2010. Neoplasia. 12(4):294-304. PMID: 20360940.
Mongiat et al. 2007. Mol Cell Biol. 27(20):7176-87. PMID: 17698584.
Add a reference
References: 3 entries
Marastoni et al. 2014. J Pathol. 232(4):391-404. PMID: 24374807.
Mongiat et al. 2010. Neoplasia. 12(4):294-304. PMID: 20360940.
Mongiat et al. 2007. Mol Cell Biol. 27(20):7176-87. PMID: 17698584.
Add a reference
Inventor Information
Inventors
|
Professor Alfonso Colombatti |
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Dr Maurizio Mongiat |
|
from National Cancer Institute CRO - Aviano |
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Dr Roberto Doliana |
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Maria Teresa Mucignat |
