![Image thumbnail for Anti-mEMILIN1 [mEMIL] monoclonal antibody](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/6615040b-dedf-4d56-ba3a-00fdae1f2119.jpg)
![Image thumbnail for Anti-mEMILIN1 [mEMIL] monoclonal antibody](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/59548eec-303b-4945-9754-d37a27e19688.jpg)
![Image thumbnail for Anti-mEMILIN1 [mEMIL] monoclonal antibody](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/a69081e4-ce4d-4777-9b8b-773819b60504.jpg)
Anti-hEMILIN2 [hEMIL2] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
Anti-mEMILIN1 [mEMIL] monoclonal antibody
Invented by Professor Alfonso Colombatti , Dr Roberto Doliana , Dr Paola Spessotto , Maria Teresa Mucignat
Invented at National Cancer Institute CRO - Aviano
- Datasheet
- References (7)
- Inventor Info
Info
| Catalogue Number | 160584 |
| Applications | ELISA IHC IF WB |
| Antigen/Gene or Protein Targets | mEMILIN1 |
| Reactivity | Mouse |
| Relevance | Emilin-1 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-1 interacts with the α4β1 integrin via the C-terminal gC1q domain. It binds pro-TGFB preventing its maturation to mature TGFB in the extracellular space, therefore influencing the regulation of blood and lymph vessels formation and maintenance. |
| Host | Rat |
| Immunogen | Recombinant murine Emilin-1 as immunizing antigen; Wistar rat as host |
| Positive Control | IgG2a kappa |
| Notes |
Storage Conditions Store at 2-8°C or aliquots at -20°C. Avoid repeated freeze-thaw cycles. Concentration Western Blot use at 2-10 μg/ml |
| Research Area | Cancer |
Anti-mMMRN2 [mMMRN2] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
Anti-mMMRN2 [mMMRN2] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
Anti-hEMILIN1 [hEMIL1] monoclonal antibody
Invented by Professor Alfonso Colombatti at National Cancer Institute CRO - Aviano
References: 7 entries
Pivetta et al. 2016. Clin Sci (Lond). 130(14):1221-36. PMID: 26920215.
Capuano et al. 2016. Hum Mutat. 37(1):84-97. PMID: 26462740.
Danussi et al. 2013. Mol Cell Biol. 33(22):4381-94. PMID: 24019067.
Danussi et al. 2012. Cancer Prev Res (Phila). 5(9):1131-43. PMID: 22827975.
Danussi et al. 2011. J Cell Biol. 195(1):131-45. PMID: 21949412.
Danussi et al. 2008. Mol Cell Biol. 28(12):4026-39. PMID: 18411305.
Zacchigna et al. 2006. Cell. 124(5):929-42. PMID: 16530041.
Add a reference
References: 7 entries
Pivetta et al. 2016. Clin Sci (Lond). 130(14):1221-36. PMID: 26920215.
Capuano et al. 2016. Hum Mutat. 37(1):84-97. PMID: 26462740.
Danussi et al. 2013. Mol Cell Biol. 33(22):4381-94. PMID: 24019067.
Danussi et al. 2012. Cancer Prev Res (Phila). 5(9):1131-43. PMID: 22827975.
Danussi et al. 2011. J Cell Biol. 195(1):131-45. PMID: 21949412.
Danussi et al. 2008. Mol Cell Biol. 28(12):4026-39. PMID: 18411305.
Zacchigna et al. 2006. Cell. 124(5):929-42. PMID: 16530041.
Add a reference
Inventor Information
Inventors
|
Professor Alfonso Colombatti |
|
|
Dr Roberto Doliana |
|
|
Dr Paola Spessotto |
|
|
Maria Teresa Mucignat |
