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T11 SCC Cell Line

Info

Catalogue Number 153675
Antigen/Gene or Protein Targets Squamous Cell Carcinoma
Synonyms SCC, Squamous cell carcinoma, T11
Host Human
Disease Keywords Cancer, Skin Cancer, Squamous Cell Carcinoma
Model Tumour line
Relevance The SCC series represent primary, recurrent and metastatic carcinoma. Availability of such a series from the same individual will facilitate genetic analysis of the malignant process.
Production Details Cutaneous SCC cell line from 48 year old male. Poorly defined primary tumour from the back with germline DNA from lymphocytes. Patient had a renal transplant and was treated with Cyclosporine, Prednisolone and Azathioprine. Patient had stopped Azathioprine treatment at the time of lesional biopsy.
Research Area Cancer
Recommended Growing Conditions Keratinocyte cell culture media supplemented with 10ng/ml EGF

References

There are 2 reference entries for this reagent.

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References: 2 entries

Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.

Europe PMC ID: 30202019


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References: 2 entries

Inman et al. 2018. Nat Commun. 9(1):3667. PMID: 30202019.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.


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