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Anti-Rad51, Polyclonal [SWE26]


Catalogue Number 151326
Applications IP WB
Antigen/Gene or Protein Targets Rad51
Reactivity Human
Relevance Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway.
Host Rabbit
Immunogen Human Rad51 N-Terminal region Peptide C. (VEEESFGPQPISRLE) linked to KLH
Formulation Whole serum
Notes Specific for Rad51 at 100ng compared to equal amount of Dmc1
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

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