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Anti-HNF1B, Polyclonal [HNF1B]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets HNF1B
Reactivity Human and Mouse
Relevance Transcription factor, probably binds to the inverted palindrome 5'- GTTAATNATTAAC-3'. This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Formulation 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal.
Method of Purification Immunogen affinity purification
Molecular Weight (kDa) 61.3 & 44.7
Research Area Epigenetics & Nuclear Signalling, Metabolism

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