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Info
Applications | ELISA IF WB |
Antigen/Gene or Protein Targets | TFAP2B |
Reactivity | Human and Mouse |
Relevance | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. |
Host | Rabbit |
Immunogen | 3 synthetic peptides (human) conjugated to KLH |
Formulation | 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal. |
Method of Purification | Immunogen affinity purification |
Molecular Weight (kDa) | 51.5 & 50.4 |
Research Area | Cell Cycle, Epigenetics & Nuclear Signalling |
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