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Anti-ErbB4 [HFR1]


Catalogue Number 151215
Applications FACS IHC IF IP WB
Antigen/Gene or Protein Targets ErbB4 (Her4, p180erbB4)
Reactivity Human and Mouse
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB4 is involved in cell growth regulation and its expression or function may be altered in human cancers.
Host Mouse
Immunogen Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein (residues 1249-1264.)
Subclass IgG2b
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 10% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 5 entries

Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.

Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.

Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.

Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

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