- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 151215 |
| Applications | FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | ErbB4 (Her4, p180erbB4) |
| Reactivity | Human and Mouse |
| Relevance | The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB4 is involved in cell growth regulation and its expression or function may be altered in human cancers. |
| Host | Mouse |
| Immunogen | Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein (residues 1249-1264.) |
| Subclass | IgG2b |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 10% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction |
References: 10 entries
Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.
Europe PMC ID: 21092257
Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.
Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.
Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.
Europe PMC ID: 20331873
Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.
Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.
Europe PMC ID: 17486069
Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.
H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Europe PMC ID: 15713896
Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.
Europe PMC ID: 9771476
Add a reference
References: 10 entries
Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.
Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.
Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.
Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.
Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.
Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.
Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.
H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.
Add a reference
Inventor Information
Inventors
|
Bill Gullick |
