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Anti-ErbB4 [HFR1]

Info

Catalogue Number 151215
Applications FACS IHC IF IP WB
Antigen/Gene or Protein Targets ErbB4 (Her4, p180erbB4)
Reactivity Human and Mouse
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB4 is involved in cell growth regulation and its expression or function may be altered in human cancers.
Host Mouse
Immunogen Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein (residues 1249-1264.)
Subclass IgG2b
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 10% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 10 entries

Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.

Europe PMC ID: 21092257

Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.

Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.

Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.

Europe PMC ID: 20331873

Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.

Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.

Europe PMC ID: 17486069

Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Europe PMC ID: 15713896

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.

Europe PMC ID: 9771476


Add a reference

References: 10 entries

Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.

Europe PMC ID: 21092257

Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.

Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.

Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.

Europe PMC ID: 20331873

Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.

Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.

Europe PMC ID: 17486069

Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Europe PMC ID: 15713896

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.

Europe PMC ID: 9771476


Add a reference

References: 10 entries

Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer.

Ko et al. 2010. Breast Cancer Res. 12(6):R100. PMID: 21092257.

Gulati et al. 2010. Diagn Pathol. 5:18. PMID: 20331873.

Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.

Sundvall et al. 2007. Oncogene. 26(48):6905-14. PMID: 17486069.

Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains.

Carón et al. 2005. Mol Cancer Ther. 4(2):243-55. PMID: 15713896.

H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types.


Add a reference


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