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Info
Applications | ELISA IF WB |
Antigen/Gene or Protein Targets | IGHMBP2 |
Reactivity | Human and Mouse |
Relevance | 5' to 3' helicase that unwinds RNA and DNA duplices in an ATPdependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder livertype antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNAbinding protein specific to 5'phosphorylated singlestranded guaninerich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'GGGCT3' motif. Interacts with tRNATyr. Stimulates the transcription of the human neurotropic virus JCV. |
Host | Rabbit |
Immunogen | 3 synthetic peptides (human) conjugated to KLH |
Molecular Weight (kDa) | 109.1 |
Research Area | Epigenetics & Nuclear Signalling, Neurobiology |
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