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Anti-IL-28R [MHLICR2A1]

Info

Applications FACS Fn
Antigen/Gene or Protein Targets IL-28R
Reactivity Human
Relevance The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity.
Host Mouse
Subclass IgG2a kappa
Research Area Cancer, Cell Signaling & Signal Transduction, Immunology

References

There are 1 reference entries for this reagent.

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References: 1 entry

Dumoutier et al. 2004. J Biol Chem. 279(31):32269-74. PMID: 15166220.


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References: 1 entry

Dumoutier et al. 2004. J Biol Chem. 279(31):32269-74. PMID: 15166220.


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