Anti-CD22 [RFB-4]
Invented at University College London
Catalogue Number | 152585 |
Applications | FACS IHC IF |
Antigen/Gene or Protein Targets | CD22 |
Reactivity | Human |
Relevance | Establishing origin of B cell malignancies, especially discriminating between immature (bone marrow type) and peripheral B cell leukaemias and lymphomas. Suitable for use as an immunotoxin against human B cell leukaemias and lymphomas. |
Host | Mouse |
Immunogen | Tonsil lymphocytes |
Subclass | IgG1 |
Formulation | PBS only |
Concentration | 1mg/ml |
Molecular Weight (kDa) | 153 |
Research Area | Adhesion, Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
Notes |
Cytoplasmic antigen of mature B lymphocytes. >90% reactivity on peripheral B cells. Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. |
Bofill et al. 1985. J Immunol. 134(3):1531-8. PMID: 3871452.
Human B cell development. II. Subpopulations in the human fetus.
Europe PMC ID: 3871452
Bofill et al. 1985. J Immunol. 134(3):1531-8. PMID: 3871452.
Human B cell development. II. Subpopulations in the human fetus.